Virbac Epi-Otic Advanced Ear Cleaner vs Zymox Otic Enzymatic Solution with 1% Hydrocortisone

Side by side on every dimension we score, so you can judge which suits your dog.

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Virbac Epi-Otic Advanced Ear Cleaner
Virbac Epi-Otic Advanced Ear Cleaner
$21.99 · ★ 4.7 (9,343)
vs
Zymox Otic Enzymatic Solution with 1% Hydrocortisone
Zymox Otic Enzymatic Solution with 1% Hydrocortisone
$28.49 · ★ 4.7 (77,633)
76
Quality
76
76
Ease of Use
76
76
Versatility
76
65
Value
65
91
Owner Satisfaction
93
Differences only
Spec
Virbac Epi-Otic Advanced Ear Cleaner#2
👑 Premium Pick
Virbac Epi-Otic Advanced Ear Cleaner
Owner rating4.7
Buy
PawBench Scoremethodology →
Quality
76
Ease of Use
76
Versatility
76
Value
65
Owner Satisfaction
91
Quality
76
Ease of Use
76
Versatility
76
Value
65
Owner Satisfaction
93
Buyer sentiment
Effectiveness Ear Cleaning Quality Scent

Buyers praise effectiveness, ear cleaning, quality and scent.

Based on 2,856 user mentions

Effectiveness Ear Relief Value for money Itching Relief

Buyers praise effectiveness, ear relief, value for money and itching relief.

Based on 20,421 user mentions

Active IngredientSalicylic acid, EDTA, chlorhexidine derivativesLP3 enzyme system + 1% hydrocortisone
Volume8 oz bottle1.25 oz bottle
ApplicationFill canal, massage base of ear 20s, let shake, wipe outer earFill canal once daily, do not pre-clean; 7–14 day course
pHBalanced (acidic, near 5.5)Balanced for enzymatic activity

* Prices are approximate and may vary. Please check the latest price on Amazon.

What owners actually say

Virbac Epi-Otic Advanced Ear Cleaner
Virbac Epi-Otic Advanced Ear Cleaner
94/100 sentiment
N=2,856
+ Effectiveness+ Ear Cleaning+ Quality+ Scent
Zymox Otic Enzymatic Solution with 1% Hydrocortisone
Zymox Otic Enzymatic Solution with 1% Hydrocortisone
96/100 sentiment
N=20,421
+ Effectiveness+ Ear Relief+ Value for money+ Itching Relief

Pros & cons

Virbac Epi-Otic Advanced Ear Cleaner

Pros

  • ✓pH-balanced, alcohol-free — won't sting inflamed canals
  • ✓Mild antimicrobial action via salicylic acid and chlorhexidine derivatives
  • ✓Vet-office benchmark — the cleaner Virbac sells to clinics worldwide
  • ✓Anti-adhesive technology reduces bacterial biofilm in the canal

Cons

  • ✗Pricier than drugstore alternatives
  • ✗Not enzymatic — chronic recurrent otitis may need Zymox instead

Zymox Otic Enzymatic Solution with 1% Hydrocortisone

Pros

  • ✓Enzymatic action (lactoperoxidase, lactoferrin, lysozyme) — handles biofilm mechanical cleaners can't
  • ✓Backed by published veterinary dermatology literature for chronic otitis
  • ✓1% hydrocortisone reduces inflammation and scratching
  • ✓OTC alternative to vet-prescribed topical antibiotics for many uncomplicated cases

Cons

  • ✗Do not clean the ear before use — the enzymes need cerumen to work on
  • ✗Not for ruptured eardrums; vet exam first if there's discharge or head tilt

As an Amazon Associate, PawBench earns from qualifying purchases.

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